Abstract: The author considers the role and the place of the countries of the South Caucasus in foreign policy strategies of the EU, the USA and NATO in the security sphere. The author studies the peculiarities of formation and development of foreign policies of these international actors towards the states of the South Caucasus, proves its special importance for security provision in the South Caucasus region. The study defines foreign policy interests of the EU, the USA and NATO in security provision in the South Caucasus. The author analyzes their foreign policy and special programs in the security sphere in relation to Azerbaijan, Armenia and Georgia. The author proves that the necessary prerequisite for security provision in the South Caucasus region is the coordination of strategies of the EU, the USA and NATO with the positions of the Russian Federation, Turkey, Iran and other interested regional actors. The research is based on the analysis of foreign policy and security strategies of the USA, the EU and NATO in relation to the South Caucasus. The author defines the specificity of American and European influence on the formation of security system in the region. The author analyzes international cooperation and studies the works of K. Gadzhiev, R. Giragosian, V. Guseinov, V, Kulik, S. Markedonov about geopolitical and security problems in the South Caucasus. The scientific novelty of the study consists in defining the place of the South Caucasus in foreign policy strategies of the countries of the region and global geopolitical actors. The author studies their conceptual approaches to the formation of regional security system. The paper actualizes the problems of studying foreign policy and security strategies of the European Union, the USA and NATO towards the South Caucasus in the context of the events of August 2008 in Georgia and Russia’s recognition of independence of South Ossetia and Abkhazia.