Abstract: The research subject is the foreign policy of the United States in Central Asia in the early 21st century. The author considers such aspects as the factors of activation of America’s policy in Central Asian direction, the role of Central Asia in America’s foreign policy in the early 21st century, and the U.S. diplomacy in Central Asia. Special attention is given to the U.S. foreign policy and its priorities in Central Asia in the second decade of the 21st century. The author applies the methods of historiography, source study, applied political science, system analysis, political analysis and geopolitical expertise. The author specifies the problems and prospects of America’s foreign policy in Central Asia in the early 21st century. The author states that the foreign policy of the U.S. in Central Asia will unavoidably change, and this transformation should be based on the refusal to solve regional problems unilaterally, and on the search for the ways of constructive cooperation with Russia and China. 

Abstract: The subject of this research is the United States  foreign policy doctrine in relation to Afghanistan and states of the Soviet Central Asia, which undergone a drastic transformation in the end of the XX – beginning of the XXI century due to geopolitical changes, associated with the collapse of the Soviet Union and the end of the Cold War. The conceptual structuring of Zbigniew Brzezinski defined content of the US foreign policy doctrine; and its major priority consisted in the attempt to establish the unipolar world and reconstitute the “neocolonial” system under the new circumstances. The main conclusion of this work consists in the scientifically substantiated positions on the fact that after the military Operation Desert Storm, the United Stated conducted the utilitarian policy in Central Asia and Afghanistan, which suggested the achievement of certain results within the framework of implemented foreign policy concept at minimum costs. Since the mid 1990’s, the United States established the “foundation” for the future “strategic breakthrough” in the region, the prerequisite for which were the economic interests, activation of the competitors, as well as the growing “Islamic threat”.