Abstract: In an extensive empirical study, the interrelationships of the marital status of managers with the peculiarities of their need-semantic sphere have been studied. Family and work are the basic, key areas in the life of each individual, therefore, identifying reliable links between these areas is important for understanding their impact on both the professional effectiveness of managers and the personality as a whole. The study was conducted among managers holding high positions in organizations and enterprises of the Siberian Federal District. The results of more than two thousand people were processed: a group of managers and a control group – "not managers". Comparisons were made between single and married respondents. This analysis is part of a large-scale work to study the specifics of the need-semantic sphere of managers. Reliable methods were used in the work: the questionnaire of motivational and semantic formations by Y.M. Orlov-B.A. Sosnovsky, the test by D.A. Leontiev "Life orientations", "Semantic differential" by C. Osgood. The processing of the results shows that managers have significantly more pronounced life-meaning attitudes and the need for affiliation, while "non-managers" emphasize self-assessment of life and assessment of the "strength" of the surrounding reality. Non-family leaders, highly appreciate the process of life and its emotional saturation, also show a higher level of locus of control. Family leaders vividly express the need for affiliation and strive to maintain harmonious relationships with people. The results of the study allow us to better understand the relationship between marital status and the needs of managers, which is important in ensuring professional efficiency and well-being. The identified phenomena can be applied to form effective management strategies, to develop individual approaches to working with different groups of employees, and to develop programs for the selection.