Abstract: After St. Petersburg was proclaimed the capital of the Russian Empire, Moscow retained status of the first capital, which gave the city some substantial advantages. On the one hand, this is remoteness of the city from the central government, while on the hand – a well-developed infrastructure of the capital city. These peculiarities strongly affected the development of the Moscow periodical press. The author notes a considerable role of Moscow as one of the leading commercial and industrial centers of the Russian Empire. The goal of this article lies in the analysis of the areas of common interests of the Russian pre-revolutionary journalism and Moscow entrepreneurship. For achieving the set goal, the author analyzes the periodical press, memoirs of the contemporaries, and certain other sources. The conclusion is made that the close interaction between the Russian periodical press and Moscow entrepreneurship begins at the time of development capitalist relations in Russia. The three directions of such cooperation are observed by the early XX century: the press as a branch of entrepreneurship; periodical press as the sociopolitical platform for the representatives of commercial and industrial world of Moscow; and Russian entrepreneurs as the object of publications. Overall, the interaction of the press and Moscow entrepreneurship contributes to the formation of a unique image of pre-revolutionary Moscow.