Abstract: Post-nonclassical nature of changes in education actualizes the need for transforming its methodological grounds. The goal of this article is to offer a new perspective of interpretation of the methodology of education, as well as trace the steps towards its post-nonclassical transformation. The research leans on the theoretical-methodological provisions of the logical-semantic approach, which focuses on the laws of conceptualization. The article explores the objective and subjective logical-semantic patterns of the work of mind characteristic to classical and post-nonclassical worldview. Congruence with the objective logic of the work of mind of methodological grounds in educational practice of the higher school is confirmed by examples. The examples show the limitations of their methodological capabilities in solving modern problems of knowledge and practice. The limitations of their methodological capabilities in solution of the relevant cognitive tasks and practice are indicated. The article suggest and analyzes the methodological principle of the subject, which determines the human-sizedness and communicative alignment of methodological system of education, which ensures its compliance with the post-nonclassical methodology of science. The author demonstrates a number of changes within the education system, which are methodologically substantiated by the principle of the subject. The highlighted logical-semantic patterns of the work of mind can be used as an instrument for understanding and explaining the components of educational process, as well as their design and management. The author proposes a nonlinear structure of the content of education. It can underlie the creation of learning model, which would consider the individual characteristics of students and fulfill the educational potential of the traditional and innovative teaching systems.