Abstract: The article presents a study of the possibilities of developing students' self-determination as a psychological resource for self-realization in the process of studying at a university. The object of the study was the phenomenon of self-determination. The subject of the study is the development of students' self-determination as a psychological resource for self-realization in the process of studying at a university. Using a theoretical analysis of approaches to the study of students’ self-determination in the learning process, the following components were identified: autonomy, self-expression, ability to self-government, meaningfulness of life, which formed the basis for the implementation of the psychological and pedagogical program as its components. The goal of the psychological and pedagogical program was to develop the components of self-determination as a psychological and pedagogical resource for the self-realization of students’ personality. The program was implemented with small groups of students of 15 people at meetings of the psychological club. The following methods were used as diagnostic research methods: “Self-determination test” by E.N. Aspen, modification of K. Sheldon’s self-determination scale; “Test of meaning in life orientations” D.A. Leontyev; test “Ability to self-government” N.M. Peysakhova. The calculation of Student's T-test for connected and disconnected samples was also applied. As a result of testing the program for the development of self-determination on the basis of the Center for Social Adaptation and Support of Psychological Health at the Federal State Budgetary Educational Institution of Higher Education "Amur State University named after Sholom Aleichem", statistically significant indicators of its effectiveness were identified, consisting in an increase in indicators of autonomy, self-expression, ability to self-government and meaningfulness of life in students participating in its implementation.