Abstract: The subject of this research is the quality of life of the indigenous minorities of the North Siberia – Dolgans and Nganasans residing in rural localities of Khatanga District of Krasnoyarsk Krai. The goal of this work is the analysis of differentiation of the subjective perception of quality of life by various segments of population residing in remote localities of the North Arctic zone of Krasnoyarsk Krai. The authors apply the developed methodology for comparative analysis of quality of life of residents of remote districts of the central taiga zone of Siberia. Methodological foundation contains a set of theoretical scientific methods, analysis of empirical data, results of surveys, observation and interviewing of the indigenous minorities in places of their residence. The scientific novelty consists in implementation of the effective method of assessment of quality of life of the communities living in harsh north environment and relating to the category of indigenous minorities of Siberia. In determination of differentiation of the various population groups in accordance with objective and subjective assessment of quality of life, the authors reveal the level of content with the quality of education, level of safety, activity of the local government, material wellbeing, quality of services in cultural sphere, environmental situation in the district, and quality of medical care.