Abstract: The subject of this research is the correlation between the structural transformations of external sector and regional economic dynamics in the conditions of active endogenous and exogenous shocks. The object of this research is a constituent of the Russian Federation – Khabarovsk Krai. The research covers the period of 16 years: from 2000 to 2015. The author examines the two scenarios of structural dynamics of the external sector of the region: inertial, suggesting maintenance of the established by now proportions between the types of economic activity that conduct commercial transactions; and innovational, contributing to the increase in regional export of highly processed portion of goods. The conducted research proves that the structure of external sector is a factor ensuring minimization of risks of the regional foreign trade cooperation from the perspective of sustainable economic dynamics. The specificity of applied methodology consists in addressing the issue of the total price of export and interregional export in terms of the separate types of economic activity (in this case, price fluctuations are reflected via changing the total price of export). The scientific novelty lies in comprehensive study of the impact of structural transformations of external sector upon the overall results of economic activity of the region in the conditions of active shocks. The scenario approach is used in varying and “intersection” of the initial data: conditions for the operation of external sector (prevalence of resource-based production; development of processing types of economic sector); “sources” of shocks (markets of different localization: global, national, regional); types of shocks (price changes; variation in consumer demand, etc.); possibility of receiving quantitative assessments of the parameters of structural transformation of the external economic sector that would ensure regional growth in the conditions of active endogenous and exogenous shocks.