Abstract: The goal of this research lies in discussing the key provisions of Carlos Moreno’s concept of 15-minute city in the context of issues caused COVID-19 pandemic. Besides the original texts by C. Moreno, the article employs the following data: 1) publications in the international scientometric databases (Scopus, WoS2) dedicated to positive effects of implementation of the concept of 15-minute city and its analogues; 2) documents of international organizations (C40 Cities, OECD, UN-Habitat3 that recommend the key vectors of sustainable urban development policy to the national governments; 3) strategies of global megacities that embarked upon practical implementation of the concept of 15-minute city. The concept at hand is based on the idea of spatial-temporal hyper-proximity of all essential functions and services of the city. The concentrated infrastructure (place of residence, work, retail, education, health, and leisure) within micro-scale spatial structures contributes to the formation of more environmentally, economically and socially sustainable cities. The global COVID-19 pandemic, which demonstrated the urgent need for “upgrading” the local living conditions, stimulated the adoption of this concept on the level of international organizations and progressive foreign megacities, as well as interest of the Russian Federation in its implementation. The conducted analysis leads to the conclusion that the model of 15-minute city, which allows effectively counteracting the new risks (including the unexpected circumstances), can be adapted to spatial peculiarities of the particular cities and needs of the residents. This article is an invitation to a scientific discussion on the prospects of transformation of the Russian megacities into a network of 15-minute cities, as well as the search for methodological solutions in the research dedicated to differentiation of the quality of urban environment in the micro-spatial dimension.