Abstract: The subject of the study is the human potential in the conditions of transformation of the socio-cultural space of the PRC. The modern anthropological crisis causes the need to search for new value foundations of human potential development and actualizes the study of cultural regional-country specifics of its implementation practices. The heterogeneous nature of the socio-cultural space of the PRC makes it necessary to know specific regional practices for developing human potential. China is forming an effective system for developing and attracting human potential within the country and in interaction with the outside world. The success of the PRC largely determines a new vision of the place and role of man in socio-cultural transformations. Human potential forms a dynamic, rapidly changing image of the socio-cultural environment in China, determining the speed and direction of internal and external modernization processes. The scientific novelty lies in the fact that in the PRC regionality acts as a cultural and spatial characteristic of activity, which in turn has a concrete expression - in practices. The philosophical and anthropological analysis of practices involves an appeal to a regionological approach that contributes to the identification of specifics at the level of regions – "internal" and "external". At the national level, the process of building human potential, which is an element of "soft power", occurs at all levels of the multilevel hierarchy of regional development management, starting from the level of large regions, ending with local-regional communities at the level of cities, towns, villages and individual enterprises.