Abstract: The author analyzes the problem of plagiarism in biomedical research. The specifics of biomedical research are considered, the primary international documents regulating the conduct of biomedical research on humans are provided, and the basic principles of such research are given. The features of plagiarism in scientific research are revealed, and its concept and varieties are considered. The specifics of the work of anti-plagiarism systems and the associated difficulties are analyzed. Plagiarism in biomedical research is a serious violation of research and publication ethics, which, if intentionally committed, leads to the discrediting of science and scientists and the illegality of research activities. The following results were obtained from the study: The use of borrowings undermines the authenticity of scientific papers and the journals publishing them, threatens the unity of the scientific process and the attitude of society toward science, and violates the literary rights of the authors of original texts and the property rights of copyright holders. Plagiarism can cause material, reputational, and moral harm to authors, such as public disclosure of data, loss of funding for ongoing research, difficulties in the professional growth of the authors of the article or the completion of research work, and in some cases, is a crime and leads to litigation.