Abstract: The subject of this research is the factors that led to formation of a negative image of “new” immigration and the occurrence of anti-immigrant moods in the United States in the last decades of the XIX – beginning of the XX centuries. The author examines the social interaction processes between the local Anglo-Saxon population and the representatives of the so-called “new” immigration from Asia and South-Eastern Europe, which replaced the traditional labor immigration from Western and Northern Europe. Special attention is given to studying the origins of hostility and xenophobia towards migrants manifested in different strata of US society – the representatives of working and middle class, academic and cultural intelligentsia, and political elite. The author concludes that all social classes showed antagonism towards the “new” immigration. Although, the rhetoric on immigration varied depending on affiliation to one or another social segment. Working and middle class were concerned about competition on the job marker, social tension and nonconformity of immigrants to the image of the “ideal American”; while the ruling elites adhered to the ingrained in public discourse idea of Anglo-Saxon supremacy, which later on became the foundation for restrictionist policy towards migrants who were trying to get established in their land.